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出版商:
Springer
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出版日期:
2025-11-14
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售價:
$10,100
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貴賓價:
9.5 折
$9,595
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語言:
英文
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頁數:
814
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裝訂:
Hardcover - also called cloth, retail trade, or trade
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ISBN:
3032031753
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ISBN-13:
9783032031754
商品描述
The oral cavity is a complex environment from an immunological perspective. Chronic exposure of the oral cavity to a plethora of microorganisms and antigens highlights the importance of the role of mucosal and systemic immune system protection against these microbes and particles. Nevertheless, dysregulation of the host-immune interaction may be the main cause of some chronic oral conditions, such as periodontal diseases. The clinical relevance of the association between oral pathological conditions and the occurrence of systemic diseases has increased clinicians' interest in understanding the underlying pathophysiologic mechanisms of this clinical relationship. On the other hand, oral manifestations are one of the primary signs of Primary and Secondary Immunodeficiency Diseases, Immune Dysregulations, and Autoimmunity in some cases; this can be an effective diagnostic approach that should not be overlooked. In this book, the mechanism of oral tolerance and probable causes of its imbalance will be addressed. As the assessment of interrelationship between immunity and oral cavity is still understudied from numerous aspects, this book aims to conduct a comprehensive evaluation of how oral diseases may be the leading cause for the development of different systemic conditions. It also explores the clinicopathological roles of the immunological factors in oral pathological conditions such as oral malignancies, chronic diseases, and other oral lesions. In addition to mucosal immunology of the oral cavity, the future perspectives of oral mucosal immunotherapy are among the emerging issues of the past decade that will be discussed comprehensively in this book.
商品描述(中文翻譯)
口腔從免疫學的角度來看是一個複雜的環境。口腔長期暴露於各種微生物和抗原中，突顯了粘膜和系統免疫系統在對抗這些微生物和顆粒方面的重要性。然而，宿主免疫互動的失調可能是某些慢性口腔疾病（如牙周病）的主要原因。口腔病理狀況與系統性疾病之間的關聯臨床意義日益增加，這引起了臨床醫生對理解這一臨床關係的潛在病理生理機制的興趣。另一方面，口腔表現是原發性和繼發性免疫缺陷疾病、免疫失調以及某些情況下自體免疫的主要徵兆之一；這可以是一種有效的診斷方法，不應被忽視。
在本書中，將探討口腔耐受的機制及其失衡的可能原因。由於免疫與口腔之間的相互關係仍然在許多方面未被充分研究，本書旨在全面評估口腔疾病如何可能成為不同系統性疾病發展的主要原因。它還探討了免疫因素在口腔病理狀況（如口腔惡性腫瘤、慢性疾病和其他口腔病變）中的臨床病理角色。除了口腔的粘膜免疫學外，口腔粘膜免疫療法的未來展望也是過去十年中出現的問題之一，將在本書中進行全面討論。
作者簡介
Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the Founder of the Universal Scientific Education and Research Network (USERN). Prof. Rezaei supervised more than two hundred research projects and designed and participated in several international collaborative projects. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than fifty international journals. He edited more than one hundred international books, presented more than a thousand lectures in congresses/meetings, and published more than 1,500 scientific papers in the international journals. Dr. Heliya Ziaei earned her Doctor of Dental Surgery (DDS) from Tehran University of Medical Sciences in 2020 and is currently completing her PhD in Craniofacial Molecular Biology at the Herman Ostrow School of Dentistry, University of Southern California. She has contributed to several interdisciplinary research projects in the areas of oral biology, craniofacial developmental science, and regenerative medicine. Dr. Ziaei served as Executive Director and Deputy of International Affairs at the Universal Scientific Education and Research Network (USERN). She has co-authored several peer-reviewed scientific articles and book chapters and has presented more than twenty lectures at academic conferences and meetings.
作者簡介(中文翻譯)
尼瑪·雷扎伊教授於德黑蘭醫科大學獲得醫學學位（MD），隨後在英國謝菲爾德大學獲得分子與遺傳醫學碩士學位（MSc）及臨床免疫學與人類遺傳學博士學位（PhD）。他還在紐卡索綜合醫院完成了兒科臨床免疫學和骨髓移植的短期研究獎學金。雷扎伊教授目前是德黑蘭醫科大學醫學院的免疫學全職教授及研究與技術副院長，並且是免疫缺陷研究中心的共同創辦人及負責人。他也是全球科學教育與研究網絡（USERN）的創始人。雷扎伊教授指導了超過兩百個研究項目，並設計及參與了多個國際合作項目。他擔任超過五十本國際期刊的編輯、編輯助理或編輯委員會成員，編輯了超過一百本國際書籍，在會議/研討會上發表了超過一千場演講，並在國際期刊上發表了超過1,500篇科學論文。 赫莉雅·齊艾教授於2020年在德黑蘭醫科大學獲得牙科外科醫學博士（DDS），目前正在南加州大學赫爾曼·奧斯特羅牙科學院完成顱面分子生物學的博士學位（PhD）。她參與了多個跨學科的研究項目，涵蓋口腔生物學、顱面發展科學及再生醫學等領域。齊艾教授曾擔任全球科學教育與研究網絡（USERN）的執行董事及國際事務副主任。她共同撰寫了多篇經過同行評審的科學文章和書籍章節，並在學術會議和研討會上發表了超過二十場演講。
