Non-Coding Rnas: Insights on the Regulatory Genome
暫譯: 非編碼RNA：調控基因組的洞察

本書提供了非編碼RNA（ncRNAs）的全面概述，這是一個關鍵但常被忽視的遺傳物質組成部分。它為ncRNAs在基因調控、表觀遺傳調控、發展與分化、細胞過程及疾病病理中的功能意義提供了新的見解。

本書遵循邏輯結構，首先介紹ncRNA的分類、生物合成途徑、調控角色及功能分析技術的最新進展。主要部分討論它們作為治療靶點的角色，並提供案例研究，突顯ncRNAs在特定生物過程或疾病中的重要性。最後，本書以對ncRNA研究未來方向和挑戰的展望作結。

由於其範疇和全面的介紹，本書不僅適合分子生物學、基因組學、轉錄組學和表觀遺傳學的研究人員，也適合學生及相關學科的人士。它提供了對ncRNA生物學的整體理解，及其對基因調控的貢獻和在健康與疾病中的角色。

Mohammad Fahad Ullah, PhD is a Professor of Biochemistry in the Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Saudi Arabia. He received his academic degrees along with a gold medal in M.Sc. (Biochemistry) from Aligarh Muslim University, India. Further, he worked as a Research Associate at Experimental Oncology Laboratory, Department of Biomedical & Diagnostic Sciences, University of Tennessee, USA. His research interests include studies on small molecules (low molecular weight compounds) in the context of their mechanistic actions and therapeutic potential against chronic diseases including cancer and diabetes. His work has also demonstrated the role of polymorphic variations in certain microRNAs in increasing the risk and susceptibility to diseases such as PCOS and cancer. He is a member of AACR (USA)/Royal Society of Chemistry (UK) and member of the editorial/reviewer board of a number of scientific journals. Dr. Ullah has more than 14 years of experience in teaching Biochemistry to the students of biological & health sciences. His academic works include 75 publications in reputed journals (WOS/h-index: 30) and four books entitled "Critical dietary factors in cancer chemoprevention" (Springer-Switzerland), "Illustrated notes on biomolecules" (Partridge-Singapore), "Nutraceuticals and Natural product Derivatives: Disease Prevention & Drug Discovery" (John Wiley & Sons-UK) and "Biocatalysis: Enzymatic Basics and Applications" (Springer-Switzerland).

Aamir Ahmad, PhD, is a Principal Investigator and Senior Scientist at Hamad Medical Corporation, Doha, Qatar. He received his academic degrees from Aligarh Muslim University, Aligarh, India with gold medals for highest marks in Department (Biochemistry) as well as Faculties of Science and Life Sciences combined. He completed his post-doctoral training at National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. He has been a member of leading cancer organizations such as the American Association for Cancer Research, Union for International Cancer Control, American Society of Clinical Oncology, Cancer Epigenetics Society, and has authored more than 250 peer-reviewed publications (h-index: 79) and 30 book chapters. He serves as Editor-in-Chief of journal 'Non-coding RNA Research' in addition to serving as editorial board member of several journals. He has edited 8 books and was ranked among the top 2% scientists globally for career-long citation impact, in the list published by Stanford University in 2020 and also in the follow-up lists 2021 through 2024, based on data from Mendeley and Scopus.

Mohammad Fahad Ullah博士是沙烏地阿拉伯塔布克大學應用醫學科學院醫學實驗室技術系的生物化學教授。他在印度阿里格爾穆斯林大學獲得生物化學碩士學位，並獲得金獎。此後，他在美國田納西大學生物醫學與診斷科學系的實驗腫瘤學實驗室擔任研究助理。他的研究興趣包括小分子（低分子量化合物）在其機制作用和對抗慢性疾病（包括癌症和糖尿病）的治療潛力方面的研究。他的工作還顯示了某些微小RNA的多態變異在增加多囊卵巢症候群（PCOS）和癌症等疾病的風險和易感性中的作用。他是美國癌症研究協會（AACR）和英國皇家化學學會的成員，並擔任多本科學期刊的編輯/審稿委員。Ullah博士在生物與健康科學領域教授生物化學已有超過14年的經驗。他的學術作品包括在知名期刊上發表的75篇論文（WOS/h-index: 30）以及四本書籍，分別為《癌症化學預防中的關鍵飲食因素》（Springer-Switzerland）、《生物分子的插圖筆記》（Partridge-Singapore）、《營養保健品與天然產品衍生物：疾病預防與藥物發現》（John Wiley & Sons-UK）和《生物催化：酶的基本原理與應用》（Springer-Switzerland）。

Aamir Ahmad博士是卡塔爾多哈哈馬德醫療公司（Hamad Medical Corporation）的首席研究員和高級科學家。他在印度阿里格爾穆斯林大學獲得學位，並因在生物化學系及科學和生命科學學院的最高成績獲得金獎。他在美國國立衛生研究院國家癌症研究所完成了博士後培訓。他曾是美國癌症研究協會、國際癌症控制聯盟、美國臨床腫瘤學會、癌症表觀遺傳學學會等領先癌症組織的成員，並發表了超過250篇同行評審的論文（h-index: 79）和30章書籍。他擔任期刊《非編碼RNA研究》的主編，並擔任多本期刊的編輯委員會成員。他編輯了8本書籍，並在2020年由史丹佛大學發布的全球科學家職業生涯引用影響力排名中位列前2%，在2021年至2024年的後續名單中也保持此排名，數據來自Mendeley和Scopus。