Workbook for Organic Synthesis: The Disconnection Approach (Paperback)

One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This "disconnection" approach to synthesis is now a fundamental part of every organic synthesis course.

Workbook for Organic Synthesis: The Disconnection Approach, 2^nd Edition

This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2^nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student's experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis.

Organic Synthesis: The Disconnection Approach, 2^nd Edition

There are forty chapters in Organic Synthesis: The Disconnection Approach, 2^nd Edition those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.

Workbook for Organic Synthesis: The Disconnection Approach, 2^nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.

有關有機合成的一種方法是逆合成分析。在這種方法中，化學家從目標分子的結構開始，逐步切斷鍵結以創建更簡單的分子。將這個過程反轉，可以從更簡單的起始物質合成目標分子的合成路線。這種「斷鍵」合成方法現在是每個有機合成課程的基礎部分。

《有機合成工作手冊：逆合成方法，第二版》

這本工作手冊提供了一套全面分級的問題，以說明和發展教科書《有機合成：逆合成方法，第二版》每個章節的主題。每個問題後面都有一個完全解釋的解答和討論。這些例子擴展了學生對有機化學家正在合成的分子類型以及他們控制合成的策略的經驗。通過解決這些例子，學生將發展他們在分析合成挑戰方面的技能，並建立一個規劃新合成的策略工具包。例子來自藥物、農藥、天然產物、費洛蒙、香料和調味品化合物、染料、單體以及更高級合成工作中使用的中間體。給出了合成每個化合物的原因。工作手冊和教科書共同提供了一個完整的逆合成分析課程。

《有機合成：逆合成方法，第二版》

《有機合成：逆合成方法，第二版》共有四十個章節，其中關於合成特定類型分子的章節與策略章節交替出現，策略章節將剛學到的方法放在更廣泛的背景中。合成章節涵蓋了製備每種類型分子的多種方法，從具有一個官能基的簡單芳香和脂肪化合物開始，進展到具有多個官能基的分子。策略章節涵蓋了選擇性、保護、立體化學等問題，並通過專門設計用於解決困難問題的試劑來發展更高級的思維。第二版中包含了更新的例子和技術，並增加了額外的材料，以達到續集《有機合成：策略和控制》所需的水平。幾個章節包含了基於作者在製藥行業給化學家的課程的大量新材料。

《有機合成工作手冊：逆合成方法，第二版》與主要教科書結合，為化學和生物化學學生提供了一個完整的逆合成分析課程，並為在工業和學術界從事有機化學工作的化學家提供了一個複習課程。

Dr Stuart Warren Department of Chemistry, University of Cambridge, UK

Dr Warren is the author of the bestselling textbooks "Organic Synthesis: The Disconnection Approach" (Wiley), "Organic Synthesis: Strategy and Control" (Wiley) and "Organic Chemistry" (OUP)

Dr Paul Wyatt

School of Chemistry, University of Bristol, UK.
Dr Wyatt is Director of Undergraduate Studies for the School of Chemistry at Bristol University and also Director of BRISTOL ChemLabS - a HEFCE Centre for Excellence in Teaching & Learning.?He is co-author, with Warren, of "Organic Synthesis: Strategy and Control"

Dr Stuart Warren 劍橋大學化學系，英國

Dr Warren 是暢銷教科書《有機合成：斷裂法》(Wiley)、《有機合成：策略與控制》(Wiley) 和《有機化學》(OUP) 的作者。

Dr Paul Wyatt

布里斯托大學化學學院，英國。

Dr Wyatt 是布里斯托大學化學學院的本科學習主任，也是 BRISTOL ChemLabS 的主任 - 這是一個卓越教學和學習的 HEFCE 中心。他與 Warren 共同撰寫了《有機合成：策略與控制》。