Advanced Mechanical Models of DNA Elasticity
暫譯: DNA 彈性之進階機械模型

Yakov M Tseytlin

  • 出版商: Academic Press
  • 出版日期: 2016-04-07
  • 售價: $4,100
  • 貴賓價: 9.5$3,895
  • 語言: 英文
  • 頁數: 316
  • 裝訂: Paperback
  • ISBN: 0128019999
  • ISBN-13: 9780128019993
  • 海外代購書籍(需單獨結帳)

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商品描述

Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic conditions on the persistence length, and dynamics with viscosity influence. It then addresses the need to understand the nature of the non-linear overstretching transition of DNA under force and why DNA has a negative twist-stretch coupling.

  • Includes coverage of 17 contemporary models of DNA mechanics with analysis
  • Provides comparison of DNA and RNA mechanical features
  • Covers advances in experimental techniques including AFM, X-ray, and optical tweezers
  • Contains extensive references for further reading

商品描述(中文翻譯)

DNA 彈性的先進機械模型》涵蓋了 17 種不同的 DNA 模型以及彈性在生物功能中的角色,並提供了廣泛的參考文獻。所描述的新型先進螺旋模型反映了分子螺旋結構與其特定性質之間的直接聯繫,包括非線性特徵和轉變。該書介紹了 DNA 力學領域的現狀,已知且廣泛使用的模型及其簡短分析,以及實驗方法和數據的涵蓋,電、磁、離子條件對持續長度的影響,以及粘度影響下的動力學。接著,它探討了在外力作用下理解 DNA 的非線性過度拉伸轉變的本質的必要性,以及為什麼 DNA 具有負扭轉-拉伸耦合。

- 包含 17 種當代 DNA 力學模型的分析
- 提供 DNA 和 RNA 機械特徵的比較
- 涵蓋包括 AFM、X 射線和光學捕捉器在內的實驗技術的進展
- 包含廣泛的參考文獻以供進一步閱讀