Protein Misfolding
暫譯: 蛋白質錯誤摺疊
Donev, Rossen
- 出版商: Academic Press
- 出版日期: 2020-01-13
- 售價: $6,190
- 貴賓價: 9.5 折 $5,881
- 語言: 英文
- 頁數: 450
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 0128177500
- ISBN-13: 9780128177501
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商品描述
Protein Misfolding, Volume 118 covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more.
- Integrates methods for studying protein misfolding, factors that trigger this process and its role in a wide spectrum of diseases and disorders
- Contains timely chapters written by well-renowned authorities in their field
- Provides data that is well supported by a number of high quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students
商品描述(中文翻譯)
《蛋白質錯誤摺疊,第118卷》涵蓋了與蛋白質錯誤摺疊相關的各種疾病和障礙,包括退行性和神經退行性疾病、心血管疾病、腎臟疾病、青光眼、癌症、囊性纖維化、戈謝病等。特定章節探討了質譜法在蛋白質摺疊和穩定性分析中的應用、生物膜在蛋白質錯誤摺疊中的關鍵角色、遺傳和環境因素如何相互作用以破壞蛋白質穩態並觸發蛋白質錯誤摺疊疾病、內在無序蛋白質形成寡聚體和大型非晶聚集體的過程、內質網壓力下的蛋白質錯誤摺疊及其在心血管和腎臟疾病中的應用等內容。
- 整合了研究蛋白質錯誤摺疊的方法、觸發此過程的因素及其在各種疾病和障礙中的角色
- 包含由該領域知名專家撰寫的及時章節
- 提供了大量高品質插圖、圖表和表格支持的數據,針對廣泛的專家、研究人員和學生受眾