Systems Biology of Cancer (Hardcover)

With over 200 types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer. Readers are provided with a realistic view of what is known and what is yet to be uncovered on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health.

迄今已經有超過200種癌症被診斷出來，全球的研究人員被迫迅速更新對癌症生物學的理解。事實上，只有研究基本細胞過程以及這些過程在癌細胞中的變化，才能最終為合理治療提供背景。《癌症系統生物學》匯集了國際專家的最新研究成果，提出了整個科學界的最終研究目標：利用系統生物學來生成基於每種癌症獨特藍圖的深入知識。讀者將獲得對基本生物過程異常、主要信號網絡失調、主要癌症變異以及利用科學知識進行有效診斷、預後和藥物發現的策略的實際了解，以改善公共健康。