Bioinformatics of the Brain
暫譯: 大腦的生物資訊學
Erciyes, Kayhan, Sevimoglu, Tuba
- 出版商: CRC
- 出版日期: 2026-05-21
- 售價: $2,520
- 貴賓價: 9.5 折 $2,394
- 語言: 英文
- 頁數: 280
- 裝訂: Quality Paper - also called trade paper
- ISBN: 1032610735
- ISBN-13: 9781032610733
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相關分類:
生物資訊 Bioinformatics
尚未上市，無法訂購
商品描述
The brain consisting of billions of neurons is probably the most complex and mysterious organ of the body. Understanding the functioning of the brain in its health and disease states has baffled the researchers working in this area for many years. The diversity of brain diseases and disorders makes the analysis of brain functions an even more challenging area of research. In vitro and in vivo studies regarding the brain may be laborious, however, bioinformatics using in silico approaches may take the burden off the experimental studies and give us a clearer perspective on disease and healthy states of the brain, its functions, and disease mechanisms.
Recent advancements in neuroimaging technologies, the development of high-performance computers and the development of software, algorithms and methods to analyze data obtained from various neuroimaging processes have opened new frontiers in neuroscience enabling unprecedented finer analysis of the brain functions. This relatively new approach of brain analysis which may be termed Bioinformatics of the Brain is the main subject of this volume aiming to provide a thorough review of various bioinformatics approaches for analyzing the functioning of the brain and understanding brain diseases such as neurodegenerative diseases, brain tumors, and neuropsychiatric disorders. Authors from various disciplines in this volume each focus on a different aspect aiming to expand our understanding of this area of research. Topics included are:
- Brain diseases and disorders
- Stem cell therapy of neurodegenerative diseases
- Tissue engineering applications of gliomas
- Brain tumor detection and modeling
- Brain tumor growth simulation
- Brain-computer interface
- Bioinformatics of brain diseases
- Graph-theoretical analysis of complex brain networks
- Brain proteomics
This book is intended to aid scientists, researchers, and graduate students in carrying out interdisciplinary research in the areas of bioinformatics, bioengineering, computer engineering, software engineering, mathematics, molecular biology, genetics, and biotechnology.
商品描述(中文翻譯)
大腦由數十億個神經元組成，可能是人體中最複雜且神秘的器官。理解大腦在健康和疾病狀態下的運作，讓從事這一領域的研究人員困惑了多年。大腦疾病和障礙的多樣性使得分析大腦功能成為一個更具挑戰性的研究領域。雖然關於大腦的體外和體內研究可能是繁瑣的，但使用生物資訊學的計算方法可以減輕實驗研究的負擔，並為我們提供更清晰的視角，了解大腦的健康狀態、功能及疾病機制。
最近在神經影像技術的進步、高效能計算機的發展，以及用於分析從各種神經影像過程中獲得數據的軟體、演算法和方法的開發，為神經科學開啟了新的前沿，使得對大腦功能的分析達到前所未有的精細程度。這種相對新穎的大腦分析方法可以稱為大腦的生物資訊學，是本書的主要主題，旨在提供對各種生物資訊學方法的全面回顧，以分析大腦的運作並理解大腦疾病，如神經退行性疾病、大腦腫瘤和神經精神障礙。本書的作者來自不同學科，各自專注於不同的方面，旨在擴展我們對這一研究領域的理解。所包含的主題有：
- 大腦疾病和障礙
- 神經退行性疾病的幹細胞療法
- 膠質瘤的組織工程應用
- 大腦腫瘤的檢測和建模
- 大腦腫瘤生長模擬
- 大腦-計算機介面
- 大腦疾病的生物資訊學
- 複雜大腦網絡的圖論分析
- 大腦蛋白質組學
本書旨在幫助科學家、研究人員和研究生在生物資訊學、生物工程、計算機工程、軟體工程、數學、分子生物學、遺傳學和生物技術等領域進行跨學科研究。
作者簡介
Kayhan Erciyes holds a B.Sc. (Hons.) in Electrical Engineering and Electronics from the University of Manchester Institute of Science and Technology, England, an M.Sc. degree in Electronic Control Engineering from the University of Salford, England and a Ph.D. degree in Computer Engineering from Ege University, Turkiye with part of the Ph.D. study realized at Edinburgh University, Scotland. He has worked as a professor in a number of institutions including Ege University, Yasar University, Uskudar University, Izmir Institute of Technology, UC Davis, Oregon State University, and California State University San Marcos. He is currently working at Computer Engineering Dept. Yaşar University, İzmir, and has published several books including Distributed and Sequential Algorithms for Bioinformatics by Springer Computational Biology Series. His research interests are broadly in graph theory and its applications in bioinformatics and brain networks, and parallel and distributed algorithms.
Tuba Sevimoglu holds a B.Sc. in Chemical Engineering from Yildiz Technical University, Turkiye, an M.Sc. degree in Industrial Engineering from Florida International University, USA, and a Ph.D. degree in Bioengineering from Marmara University, Turkiye. She is currently a professor of Bioengineering at University of Health Sciences in Istanbul, Turkiye. Her research interests include bioinformatics approaches to analyzing big data, gene expression, biological networks and the bioinformatics of genetic, neurodegenerative, and autoimmune diseases.
作者簡介(中文翻譯)
凱漢·厄爾基耶斯 (Kayhan Erciyes) 擁有英國曼徹斯特科技大學的電機工程與電子學榮譽學士學位、英國索爾福德大學的電子控制工程碩士學位，以及土耳其艾傑大學的計算機工程博士學位，其中部分博士研究是在蘇格蘭的愛丁堡大學進行的。他曾在多所機構擔任教授，包括艾傑大學、雅莎大學、烏斯屈達大學、伊茲密爾科技大學、加州大學戴維斯分校、俄勒岡州立大學和加州州立大學聖馬可斯分校。目前，他在雅莎大學的計算機工程系工作，並出版了多本書籍，包括施普林格計算生物學系列的《生物信息學中的分佈式和序列算法》。他的研究興趣廣泛涵蓋圖論及其在生物信息學和大腦網絡中的應用，以及並行和分佈式算法。
圖巴·塞維莫格魯 (Tuba Sevimoglu) 擁有土耳其伊斯坦堡的伊爾迪茲科技大學的化學工程學士學位、美國佛羅里達國際大學的工業工程碩士學位，以及土耳其馬爾馬拉大學的生物工程博士學位。她目前是土耳其伊斯坦堡健康科學大學的生物工程教授。她的研究興趣包括利用生物信息學方法分析大數據、基因表達、生物網絡，以及遺傳性、神經退行性和自體免疫疾病的生物信息學。
