Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration

本書探討了快速發展的嘌呤能信號傳遞領域，並檢視ATP及其他核苷酸的受體以及腺苷的受體在神經傳遞、突觸活動控制、增殖、分化及中樞神經系統細胞死亡調控中的作用。本書重點關注嘌呤能受體和外核苷酸酶在體外和體內的胚胎及成人神經生成中的參與，以及在突觸傳遞和病理生理學中的角色。此外，各章節還討論了包括帕金森病、阿茲海默病、自閉症、情緒障礙和癲癇等各種腦部疾病，並在嘌呤能信號傳遞及其臨床方面的背景下進行分析。本書還重視嘌呤能受體激動劑的開發。這本書對當前科學狀態進行了批判性回顧，對於希望參與或已經參與此領域的科學家和學生都將非常有用。此外，本書也針對神經科學家、醫生及業界專業人士，幫助他們在這個令人興奮且快速成長的神經科學領域中更新知識。

Prof. Henning Ulrich studied Biology at the Universities of Hamburg and Kiel (Germany) and performed his master thesis in Biochemical Parasitology, followed by a PhD in Biochemistry and Neuroscience at the University of Hamburg, Germany. He completed his training by postdoctoral research at the Centre of Molecular Neurobiology at the University of Hamburg and Cornell University, NY, the latter one financed by a fellowship of the American Heart Association. He came to the Institute of Chemistry at the Sao Paulo University as a visiting scientist, where he was then appointed as faculty member. He is Full Professor and head of the Laboratory of Neuroscience. He is internationally recognized for his work on purinergic signaling, stem cells and mechanisms of neurogenic differentiation and neurodegeneration. Dr. Ulrich has published more than 250 papers in peer-reviewed journals (H-factor of 50, ca. 9,500 citations), 4 books (3 of them published with Springer), 30 book chapters and participated in 4 patents. His research results were commented in major Brazilian newspapers. His is editorial board member of renowned journals, Associate Editor of Cytometry A, Academic Editor of PLoS ONE, Associate Editor of Purinergic Signalling, Section Editor of Stem Cell Reviews & Reports and Life.
Prof. Peter Illes has studied medicine in Budapest at the Semmelweis University of Medicine and has been Associate Professor in the Department of Pharmacology of the University of Freiburg and afterwards Full Professor and Director of the Department of Pharmacology of the University of Leipzig, Germany. Presently he holds a Chair at the Chengdu University of Traditional Chinese Medicine, China. He has obtained numerous awards and distinctions; he is also member of several professional organizations such as the Academia Europaea or the Czech Learned Society. He has been awarded by honorary Doctorates in Budapest, Hungary, and Chengdu, China and with a number of Honorary Professorships. He is neuroscientist with special emphasis on two types of ATP-sensitive receptors, belonging to the P2X3 and P2X7 class. These receptors regulate pain sensation and neurodegenerative processes, respectively. Dr. Illes has published more than 400 papers in peer-reviewed journals (H-factor of 60) and edited 3 books. He has been or is presently editorial board member of about 10 journals and is Editor-in-Chief of the Section Molecular Pharmacology of the International Journal of Molecular Sciences (IF=4.556).
Dr. Talita Glaser studied Biology at São Paulo University (Brazil) and performed her PhD thesis in Biochemistry and Neuroscience at the same university. She completed her training during PhD in Kyoto University followed by postdoctoral research training at the University of São Paulo and Harvard Medical School. She is actually a postdoctoral fellow at the laboratory of Prof. Henning Ulrich at the University of São Paulo. Even asa young investigator, her work on purinergic signalling and stem cells are well cited and known internationally. Dr. Glaser has published over 40 papers in peer-reviewed journals and (H-factor of 19, ca. 1284 citations) 6 book chapters. The results of her research were commented on by major Brazilian newspapers.

亨寧·烏爾里希教授在德國漢堡和基爾大學學習生物學，並在生化寄生蟲學領域完成碩士論文，隨後在漢堡大學獲得生物化學和神經科學的博士學位。他在漢堡大學的分子神經生物學中心和美國康奈爾大學進行了博士後研究，後者的研究經費由美國心臟協會的獎學金提供。他作為訪問科學家來到聖保羅大學化學研究所，隨後被任命為教職員。他是全職教授並擔任神經科學實驗室的主任。他因在嘌呤能信號傳遞、幹細胞及神經源性分化和神經退行性變化機制方面的研究而享有國際聲譽。烏爾里希博士在同行評審的期刊上發表了超過250篇論文（H因子為50，約9,500次引用），出版了4本書（其中3本與Springer合作出版），撰寫了30篇書章，並參與了4項專利。他的研究成果曾在巴西主要報紙上被報導。他是多本知名期刊的編輯委員會成員，擔任《Cytometry A》的副編輯、《PLoS ONE》的學術編輯、《Purinergic Signalling》的副編輯，以及《Stem Cell Reviews & Reports》和《Life》的區域編輯。

彼得·伊萊斯教授在匈牙利布達佩斯的塞梅爾維斯醫科大學學習醫學，曾擔任弗賴堡大學藥理學系的副教授，之後成為德國萊比錫大學藥理學系的全職教授和主任。目前，他在中國成都中醫藥大學擔任教授。他獲得了多項獎項和榮譽，並且是多個專業組織的成員，如歐洲學院和捷克學術學會。他在匈牙利布達佩斯和中國成都獲得了榮譽博士學位，並獲得多個榮譽教授職位。他是一位神經科學家，特別專注於兩種類型的ATP敏感受體，屬於P2X3和P2X7類別。這些受體分別調節疼痛感知和神經退行性過程。伊萊斯博士在同行評審的期刊上發表了超過400篇論文（H因子為60），並編輯了3本書。他曾擔任或目前擔任約10本期刊的編輯委員會成員，並擔任《國際分子科學期刊》分子藥理學部分的主編（影響因子=4.556）。

塔莉塔·格拉塞博士在巴西聖保羅大學學習生物學，並在同一所大學完成生物化學和神經科學的博士論文。她在京都大學完成了博士期間的培訓，隨後在聖保羅大學和哈佛醫學院進行了博士後研究培訓。她目前是聖保羅大學亨寧·烏爾里希教授實驗室的博士後研究員。即使作為一名年輕研究者，她在嘌呤能信號傳遞和幹細胞方面的研究已在國際上受到廣泛引用和認可。格拉塞博士在同行評審的期刊上發表了超過40篇論文（H因子為19，約1,284次引用）和6篇書章。她的研究成果曾在巴西主要報紙上被報導。