Innovation in Life Sciences: The Digital Revolution

生命科學產業正面臨數據驅動方法的數位革命，徹底顛覆價值鏈的各個方面，如基因療法、個體化醫療、先進細胞和組織工程、工業4.0、人工智慧、區塊鏈、數位孿生、醫療物聯網（IoMT）和醫療軟體（SaMD）。我們的編輯專書提供了對這場席捲整個產業的數位破壞的全面報導。從藥物研發到製造和生命週期管理，我們探討了數位化的深遠影響。我們的作者深入探討了開放創新、科幻原型和醫學影像和醫療保健的數位轉型。本書不僅僅是理論，還提供了實用的見解。我們提供以商業為導向的案例研究，探討併購議題、風險投資和其他投資者觀點，並強調數位化的角色。此外，我們還探討了由這場數位革命引發的文化和倫理挑戰，以及所需的管理變革。

Hans Henning von Horsten is a Professor for Industrial Biomanufacturing at HTW-Berlin-University of Applied Sciences (Germany) and Founding Dean of theFaculty of Pharmaceutical Engineering and Technology at the German International University of Applied Sciences in Cairo (Egypt) . Currently, he is serving as the deputy manager for the Life Science Management study program at HTW Berlin. Prior to joining HTW-Berlin he was in charge of project and technology management within the Cell Line Development Business Unit of ProBioGen AG, an internationally operating Contract Development and Manufacturing Organization (CDMO) for the biopharmaceutical industry. In this role, he was among the key inventors of ProBioGen's GlymaxX antibody engineering technology that was outlicensed to Boehringer-Ingelheim, Novartis, Thermo-Fisher Scientific, Bayer, Roche, Abbvie and several other drug developers. He is co-inventor of several patents for the biomanufacturing business.

Philipp Plugmann has been doing multidisciplinary work for the last 20 years in parallel to practicing as a dentist in his own clinic in Leverkusen (Germany). He is also Full Professor for Interdisciplinary Periodontology and Prevention at SRH University of Applied Health Sciences. His first book on innovation in medical technology published in 2011 was reviewed by Cisco. His second book on innovation published with Springer in 2018 got more than 50,000 chapter downloads in its first fifteen months. Previously, he held multiple adjunct faculty appointments for more than twelve years and has won multiple teaching awards. He also holds an MBA, a MSc in Business Innovation, a MSc in Periodontology and Implant Therapy (DGParo) and is currently pursuing his third doctorate. Plugmann has given research talks in the field of innovation at Conferences at Harvard Business School, Berkeley Haas School of Business, Max Planck Institute for Innovation and Competition, and Nanyang Tech University, Singapore. Philipp Plugmann is a serial entrepreneur and advisor to several companies, including a global technology consultancy - DataArt.

Moritz von Stosch is a thought leader in the area of hybrid modeling for bioprocess development and manufacturing. He is the co-author of more than 40 scientific publications, including the Book "Hybrid Modelling in Process Industries". He is the Chief Innovation Officer at DataHow AG and Managing Director of DataHow LDA (Switzerland). Prior to joining DataHow, Moritz led the Process Systems Biology & Engineering Centre of Excellence at GSK Vaccines, for which he received an Innovation Performance and Trust award and was nominated a change catalyst. He lectured at Newcastle University (England), holds a PhD in Biochemical Engineering from University of Porto (Portugal) and received a Dipl.Ing. in Chemical Engineering from RWTH Aachen University (Germany).

Avo Schönbohm自2010年起擔任柏林經濟法學院（德國）的商業管理教授。他在國際研究領域的專業知識包括（戰略）績效管理、企業遊戲化和數字轉型。他已經撰寫了50多篇著作。在越南、波蘭、法國和瑞士的國際教學任務豐富了他的教學風格和學術視野。在加入柏林經濟法學院之前，Avo在機床行業擔任了多個國際職位，並在2010年以20億歐元的銷售額擔任Voith Paper GmbH的副總裁戰略規劃。他於2016年創立了LUDEO商業代理機構，以將遊戲思維引入商業生活，從而提升各行業組織的行為和績效。

Hans Henning von Horsten是柏林應用科學大學（德國）的工業生物製造學教授，也是德國國際應用科學大學開羅分校藥學工程與技術學院的創始院長。目前，他擔任柏林應用科學大學生命科學管理學研究計劃的副經理。在加入柏林應用科學大學之前，他負責ProBioGen AG的細胞系開發業務部門的項目和技術管理，該公司是一家國際運營的生物製藥行業合同開發和製造組織（CDMO）。在這個角色中，他是ProBioGen的GlymaxX抗體工程技術的主要發明人之一，該技術已經授權給了勃林格殷格翰、諾華、熱電科學、拜耳、羅氏、艾伯維和其他幾家藥物開發商。他是生物製造業的幾項專利的共同發明人。

Philipp Plugmann在過去20年中從事多學科工作，同時在德國Leverkusen擁有自己的牙科診所。他還是SRH應用健康科學大學的跨學科牙周病學和預防學教授。他於2011年出版的第一本關於醫療技術創新的書籍獲得了思科的評論。他於2018年與Springer合作出版的第二本創新書籍在前15個月內下載了超過50,000章節。此前，他擔任多個附屬教職職位超過十二年，並獲得多個教學獎項。他還擁有工商管理碩士學位、商業創新碩士學位、牙周病學和植入治療碩士學位（DGParo），目前正在攻讀第三個博士學位。Plugmann在創新領域的研究演講在哈佛商學院、伯克利哈斯商學院、馬克斯普朗克創新和競爭研究所以及新加坡南洋理工大學的會議上發表過。Philipp Plugmann是一位連續創業家，也是數家公司的顧問，包括全球技術咨詢公司DataArt。

Moritz von Stosch是生物過程開發和製造領域的思想領袖。他是40多篇科學論文的合著者，包括《過程工業中的混合建模》一書。他是DataHow AG的首席創新官，也是DataHow LDA（瑞士）的總經理。在加入DataHow之前，Moritz領導了GSK疫苗的過程系統生物學和工程卓越中心，並因此獲得創新表現和信任獎，並被提名為變革催化劑。他曾在紐卡斯爾大學（英國）講授課程，並在波爾圖大學（葡萄牙）獲得生物化學工程博士學位，以及在亞琛工業大學（德國）獲得化學工程學士學位。