Introduction to Biological Networks (Hardcover)

Alpan Raval, Animesh Ray

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商品描述

The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap, Introduction to Biological Networks provides a thorough introduction to genomics-inspired network biology for physical scientists and biologists involved in interdisciplinary research.

 

The book focuses on the concept of molecular and genetic interaction networks as a paradigm for interpreting the complexity of molecular biology at a genomic scale. The authors describe the experimental methods used to discover and test networks of interaction among biological molecules. They also present computational methods for predicting the interaction networks, discuss general mechanisms of network formation and evolution, and explore the application of network approaches to important problems in biology and medicine.

 

With many examples throughout and clear explanations of key concepts, this book is the first to offer a broad treatment of genomics-inspired network biology with sufficient mathematical and biological rigor. It gives readers a conceptual understanding of this burgeoning scientific field.

商品描述(中文翻譯)

新興的基因組學啟發網絡生物學研究領域缺乏一本介紹性的書籍,能夠讓物理/計算科學家和生物學家獲得對當前思想的一般但足夠嚴謹的觀點。填補這一空白,《生物網絡導論》為從事跨學科研究的物理科學家和生物學家提供了對基因組啟發的網絡生物學的全面介紹。

該書聚焦於分子和基因相互作用網絡的概念,作為解釋基因組尺度下分子生物學複雜性的範例。作者描述了用於發現和測試生物分子間相互作用網絡的實驗方法。他們還介紹了預測相互作用網絡的計算方法,討論了網絡形成和演化的一般機制,並探討了將網絡方法應用於生物學和醫學中的重要問題。

本書通過許多示例和對關鍵概念的清晰解釋,是第一本提供足夠數學和生物學嚴謹性的基因組啟發網絡生物學廣泛論述的書籍。它使讀者對這個新興的科學領域有了概念性的理解。