The Microbiome's Impact on the Brain: A Paradigm Shift in Neurodegenerative Research
暫譯: 微生物組對大腦的影響：神經退行性研究的範式轉變

Rahman, MD Habibur, M, Muhasina K.

The Microbiome's Impact on the Brain: A Paradigm Shift in Neurodegenerative Research
  • 出版商: Springer
  • 出版日期: 2026-05-12
  • 售價: $9,270
  • 貴賓價: 9.5 折 $8,806
  • 語言: 英文
  • 頁數: 391
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9819574935
  • ISBN-13: 9789819574933

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This book explores the rapidly advancing field of gut-brain interactions, with a particular focus on the emerging evidence linking the gut microbiome to neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, cerebral palsy, and amyotrophic lateral sclerosis (ALS). As scientific discoveries continue to illuminate how gut microorganisms influence brain structure and function, this work examines the mechanisms through which microbial imbalance contributes to disease onset and progression. By integrating cutting-edge findings on neuroinflammation, immune modulation, metabolic signaling, and neurotransmitter regulation, the book provides a comprehensive analysis of how the gut microbiome may act not only as a contributing factor but also as a promising therapeutic target. Each chapter highlights how disturbances in gut microbial ecology can trigger neuroinflammation, cognitive impairment, and motor neuron degeneration, while also presenting emerging therapeutic strategies including probiotics, prebiotics, dietary interventions, and fecal microbiota transplantation. Ultimately, this book offers an optimistic perspective on the development of microbiome-based, personalized interventions that hold the potential to transform the prevention and treatment of neurological disorders.

商品描述(中文翻譯)

本書探討了快速發展的腸腦互動領域，特別關注腸道微生物組與神經退行性疾病之間的關聯性，如阿茲海默症（Alzheimer's disease）、帕金森病（Parkinson's disease）、腦性麻痺（cerebral palsy）和肌萎縮側索硬化症（amyotrophic lateral sclerosis, ALS）。隨著科學發現不斷揭示腸道微生物如何影響大腦結構和功能，本書檢視了微生物失衡如何促進疾病的發生和進展的機制。通過整合有關神經炎症、免疫調節、代謝信號傳遞和神經傳遞物質調控的前沿研究，本書提供了腸道微生物組不僅作為一個促成因素，還作為一個有前景的治療目標的全面分析。每一章節都強調腸道微生物生態的擾動如何引發神經炎症、認知障礙和運動神經元退化，同時介紹了包括益生菌（probiotics）、益生元（prebiotics）、飲食干預和糞便微生物移植（fecal microbiota transplantation）等新興治療策略。最終，本書提供了一個樂觀的視角，關於基於微生物組的個性化干預的發展，這些干預有潛力改變神經系統疾病的預防和治療。

作者簡介

Md. Habibur Rahman, RPh, Ph.D.

Md. Habibur Rahman is a Registered Pharmacist and a member of the Novel Global Community Education Foundation (Australia). He earned his Ph.D. in Medical Science and has contributed his expertise to several leading pharmaceutical organizations. His research is primarily focused on neuroscience, particularly the molecular mechanisms underlying clinical dementia, with emphasis on biomarker discovery and targeted diagnostic strategies. In addition to his neuroscience work, Dr. Rahman is an expert in molecular biology, with extensive experience in gene expression analysis, oxidative stress pathways, and neuroinflammation. He has been recognized among the top 2% of scientists worldwide (Stanford University, citation-based global ranking) for his impactful contributions. Dr. Rahman is also an active scientific communicator and public speaker, frequently presenting at international conferences and academic forums. He serves as a peer reviewer for several high-impact journals and is involved in multiple ongoing research collaborations in neuroscience and molecular medicine.

MUHASINA KM, M Pharm, Ph D
Department of Pharmaceutical Analysis, Prime College of Pharmacy, Palakkad, Kerala, India.

Dr Muhasina K M is a dedicated academician and researcher currently serving as an Associate Professor at Prime College of Pharmacy, affiliated with Kerala University of Health Sciences and Pharmacy Council of India, shaping the next generation of pharmacy professionals through her expertise and commitment to excellence. With a strong academic foundation and specialisation in the field, she has developed a keen research interest in novel drug delivery systems, natural-product-based therapeutics and cancer biology. Her scholarly work reflects a balance of scientific rigour and innovative thinking, contributing to the advancement of Pharmacy education and applied research.

She has actively participated in various conferences and gained loud applause for her research contributions, and she is actively engaged in interdisciplinary research communities. Her contributions extend beyond academics into mentorship and curriculum development, where she emphasises hands-on learning, critical thinking and research curiosity among students. As an aspiring academician and researcher, she continues to explore emerging trends in pharmaceutical sciences, with a vision to support evidence-based advancement in health care.

作者簡介(中文翻譯)

Md. Habibur Rahman, RPh, Ph.D.
Md. Habibur Rahman 是一位註冊藥劑師，也是新全球社區教育基金會（澳大利亞）的成員。他獲得了醫學科學的博士學位，並將其專業知識貢獻給幾個領先的製藥組織。他的研究主要集中在神經科學，特別是臨床癡呆症的分子機制，強調生物標記的發現和針對性的診斷策略。除了神經科學的工作外，Rahman 博士還是分子生物學的專家，擁有基因表達分析、氧化壓力途徑和神經炎症方面的豐富經驗。他因其有影響力的貢獻而被認定為全球前 2% 的科學家（斯坦福大學，基於引用的全球排名）。Rahman 博士還是一位活躍的科學傳播者和公共演講者，經常在國際會議和學術論壇上發表演講。他擔任多本高影響力期刊的同行評審，並參與多個神經科學和分子醫學的持續研究合作。

MUHASINA KM, M Pharm, Ph D
印度喀拉拉邦帕拉卡德市，Prime College of Pharmacy 藥物分析系。
Muhasina K M 博士是一位專注的學者和研究人員，目前擔任 Prime College of Pharmacy 的副教授，該學院隸屬於喀拉拉健康科學大學和印度藥學委員會，通過她的專業知識和對卓越的承諾，培養下一代藥學專業人才。她擁有堅實的學術基礎和專業領域的專長，對新型藥物傳遞系統、基於天然產品的治療和癌症生物學產生了濃厚的研究興趣。她的學術工作反映了科學嚴謹性和創新思維的平衡，為藥學教育和應用研究的進步做出了貢獻。

她積極參加各種會議，並因其研究貢獻而獲得熱烈掌聲，並積極參與跨學科研究社群。她的貢獻超越了學術界，還包括導師指導和課程開發，強調在學生中培養實踐學習、批判性思維和研究好奇心。作為一名有抱負的學者和研究人員，她持續探索藥學科學中的新興趨勢，旨在支持基於證據的醫療進步。

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