From the Maluku to Molecules: How Natural Substances Write History
暫譯: 從馬魯古到分子:自然物質如何書寫歷史
Kayser, Oliver
- 出版商: Springer
- 出版日期: 2024-11-29
- 售價: $2,960
- 貴賓價: 9.5 折 $2,812
- 語言: 英文
- 頁數: 574
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 3662699222
- ISBN-13: 9783662699225
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相關分類:
化學 Chemistry
海外代購書籍(需單獨結帳)
相關主題
商品描述
Natural products are a marvel of evolution. Plants are chemical factories and have produced a vast number of highly diverse and interesting natural substances with their extraordinary properties, which we humans have been using for centuries to relieve and cure diseases. At the latest since the discovery of penicillin, natural substances have become an important source of medicines, but we know only very few of the presumably many millions that are still waiting to be discovered. Important antibiotics, immunosuppressants, anticancer agents, hormones, and antiviral agents are among the natural products. But do natural products still matter in the age of biotechnology and genetic engineering? Yes, more than ever, because medicinal chemists draw creative inspiration for their syntheses from nature to develop the next blockbuster in medicine.
Oliver Kayser tells the story of natural products and medicinal plants in this book in a highly informative and amusing way from a new perspective. He explores how natural products from naturopathy gave birth to the pharmaceutical industry, how they shaped our society as medicines and remedies, enabled wars, and paved the way to Nobel Prizes. The author paints a fascinating panorama of natural product chemistry in plants, microorganisms, and animals. Starting with the first isolations at the beginning of the industrial revolution, he leads us with the ideas and enthusiasm of many scientists into the modern era of drug testing, computer chemistry, and the highly successful serendipitous discoveries of active ingredients. Natural product research in the laboratory has an enormous impact on our lives today. The author offers a glimpse over the shoulder of how the search for the new drugs of tomorrow works today. This book is the ultimate book from the pen of a scientist deeply rooted in research, providing the reader with an enlightening and at the same time entertaining insight into how scientists think and how arduous research can be.
商品描述(中文翻譯)
天然產品是進化的奇蹟。植物是化學工廠,產生了大量高度多樣化且有趣的天然物質,這些物質擁有非凡的特性,我們人類幾個世紀以來一直在使用它們來緩解和治療疾病。自從青黴素的發現以來,天然物質已成為藥物的重要來源,但我們知道的僅僅是極少數,可能還有數百萬種天然物質在等待被發現。重要的抗生素、免疫抑制劑、抗癌劑、荷爾蒙和抗病毒劑都屬於天然產品。但在生物技術和基因工程的時代,天然產品仍然重要嗎?是的,比以往任何時候都更重要,因為藥物化學家從自然中汲取創意靈感,開發下一個醫學上的暢銷藥物。
奧利佛·凱瑟(Oliver Kayser)在這本書中以高度資訊性和趣味性的方式,從新的視角講述了天然產品和藥用植物的故事。他探討了自然療法中的天然產品如何催生了製藥產業,如何作為藥物和療法塑造了我們的社會,促成了戰爭,並鋪平了通往諾貝爾獎的道路。作者描繪了植物、微生物和動物中的天然產品化學的迷人全景。從工業革命初期的首次分離開始,他帶領我們通過許多科學家的想法和熱情,進入現代藥物測試、計算化學和高度成功的偶然發現活性成分的時代。實驗室中的天然產品研究對我們今天的生活產生了巨大的影響。作者讓我們窺見當今尋找明天新藥的過程。這本書是來自一位深耕於研究的科學家的終極著作,為讀者提供了啟發性的同時又娛樂性的洞見,讓人了解科學家是如何思考的,以及艱辛的研究過程。
作者簡介
Oliver Kayser is a pharmacist, internationally recognized professor, and natural product researcher at TU Dortmund. He is the author of many scientific publications and textbooks. His great interest lies in medicinal plants and natural products that have fostered the birth of modern drugs. The focus of his work is on researching the biosynthesis of medically significant natural products in plants, which today serve as lead structures for new active ingredients in cancer medicine, neurological diseases, and as antibiotics.
作者簡介(中文翻譯)
奧利佛·凱瑟是一位藥劑師、國際知名教授及多特蒙德大學的天然產品研究員。他是許多科學出版物和教科書的作者。他對於藥用植物和促進現代藥物誕生的天然產品有著濃厚的興趣。他的研究重點在於探討植物中具有醫療意義的天然產品的生物合成,這些產品如今作為癌症醫學、神經疾病及抗生素的新活性成分的先導結構。